{"id":41806,"date":"2024-10-28T07:00:00","date_gmt":"2024-10-28T06:00:00","guid":{"rendered":"https:\/\/www.teoresigroup.com\/?post_type=projects&#038;p=41806"},"modified":"2024-10-25T14:42:00","modified_gmt":"2024-10-25T12:42:00","slug":"aisha-2","status":"publish","type":"projects","link":"https:\/\/teoresi.sixeleven.it\/de\/projects\/aisha-2\/","title":{"rendered":"Hiantis"},"content":{"rendered":"\n\t\n\t\n\t\t<div id=\"block_047c22057b8c85183db926c227872b2e\" class=\"hero-image\">\n\t\t\t<div class=\"image-hero-container row expanded isdark\">\n\n\t\t\t\t\t\t\t\t\t<div class=\"top absolute z-10 pin-t pin-l xsmall-pt-4 xsmall-pl-4 small-pt-6 small-pl-6 pt-12 pl-12\">\n\t\t\t\t\t\t<span class=\"toptitle color-white title-line orange\">projects<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t\t<!-- Icona centrale per small -->\n\t\t\t\t<div class=\"hero-icon middle hide-for-medium absolute z-10 pin-l xsmall-pl-4 small-pl-6 pl-12\">\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\n\t\t\t\t<!-- Blocco Icona + Titolo per medium-up -->\n\t\t\t\t<div class=\"bottom show-for-medium z-10 absolute pin-b pin-l xsmall-pb-4 xsmall-pl-4 pb-12 pl-12\">\n\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<h1 class=\"hero-title title mb-0 dot-after\">Hiantis<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h2 class=\"subtitle h4 mt-2 color-grey-lighter\">A Software Revolutionizing Molecular Diagnostics<\/h2>\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\n\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t<!-- Versione senza parallasse -->\n\t\t\t\t\t<div class=\"hero-bg bg-img b-lazy\" data-src = \"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2024\/09\/dddddddddddddd.jpg\" ><\/div>\n\n\t\t\t\t\n\t\t\t\t<div class=\"hero-filter\"><\/div>\n\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\t<!-- Titolo fuori Hero per small -->\n\t\t<div class=\"row sezione hide-for-medium\">\n\n\t\t\t<div class=\"column\">\n\t\t\t\t\t\t\t\t\t<h1 class=\"hero-title title mb-0 dot-after\">Hiantis<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<h2 class=\"subtitle h4 mt-2\">A Software Revolutionizing Molecular Diagnostics<\/h2>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t<\/div>\n\n\t\n\n\n\r\n    \r\n    <div id=\"block_6d1043bcbaec0cc558d6bad052c8a1a6\" class=\"breadcrumbs row sezione\">\r\n        <div class=\"column small-12 fs-xsmall\">\r\n            <span><span><a href=\"https:\/\/teoresi.sixeleven.it\/de\/\"><span class=\"tg-homepage-icon\"><\/span><\/a><\/span><\/span>        <\/div>\r\n    <\/div>\r\n\r\n\n\n\r\n\t\r\n\t\r\n\t\t<div id=\"block_052dd54736de633dc04fb93f53cff292\" class=\"_project-ownership-row wp-block-columns pt-8 small-pl-0 small-pr-0 xsmall-pl-0 xsmall-pr-0 medium-pl-24 medium-pr-24 pl-32 pr-32 row flex align-middle \">\r\n\t\t\t<div class=\"_project-ownership-col wp-block-column column small-12 flex align-middle pl-0 pr-0 pb-6\" style=\"border-bottom: 1px solid #ececec;\">\r\n\r\n\t\t\t\t<span class=\"inline-block h5 mb-0 pr-3\" style=\"border-right: 1px solid #ececec;\">A Teoresi Group project<\/span>\r\n\t\t\t\t<div class=\"_ownership-logos-wrap flex-1 flex overflow-hidden\" style=\"gap:2rem; padding-left:2rem; padding-right:2rem; overflow-x: scroll;\">\r\n\r\n\t\t\t\t\t\t\t\t\t\t\t<figure class=\"_ownership-logo\" style=\"\" data-url=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2023\/12\/hf-logo-positive.svg\" data-size=\"0x0\" ><img decoding=\"async\" class=\"b-lazy \" style=\"\" src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/themes\/FoundationPress\/studio42\/img\/loader-320-free.svg\" itemprop=\"thumbnail\" data-src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2023\/12\/hf-logo-positive.svg|https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2023\/12\/hf-logo-positive.svg|https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2023\/12\/hf-logo-positive.svg\" alt=\"HiFuture A Teoresi Group Company\" width=\"100%\" height=\"100%\" \/><figcaption class=\"image-caption block\"><\/figcaption><\/figure>\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t<\/div>\r\n\t\t<\/div>\r\n\r\n\t\r\n\n\n\n<div class=\"wp-block-columns small-pl-0 small-pr-0 xsmall-pl-0 xsmall-pr-0 medium-pl-24 medium-pr-24 pl-32 pr-32 row sezione\">\n<div class=\"wp-block-column small-12 medium-4 large-4 pr-12\">\n<h5 class=\"wp-block-heading\">Project<\/h5>\n\n\n\n<p>The project, now completed on the HiFuture side, aimed to develop a fast software solution for interpreting and managing the results of gene amplification for the papillomavirus. This was achieved using two innovative kits (HPV OncoPredict SCR and QT), which are based on the use of multi-parametric and combined Real-Time PCR technology. These kits allow for qualitative or quantitative, genotype-specific typing of 13 or 12 oncogenic HPV genotypes, as part of cervical cancer screening and follow-up. The kits operate on two analysis levels (screening and typing), for both manual and automated use with varying sample sizes. For these reasons, the client requested the development of software that is flexible in terms of input raw data format and capable of automated analysis.&nbsp;<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column small-12 medium-4 large-4 pr-12\">\n<h5 class=\"wp-block-heading\">Client<\/h5>\n\n\n<figure class=\"wp-block-figure \" style=\"\" data-url=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2024\/10\/logo-hiantis-1.png\" data-size=\"224x225\" ><img decoding=\"async\" class=\"b-lazy wp-block-image \" style=\"\" src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/themes\/FoundationPress\/studio42\/img\/loader-full.svg\" itemprop=\"thumbnail\" data-src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2024\/10\/logo-hiantis-1.png\" alt=\"logo-hiantis-1\" width=\"224\" height=\"225\" \/><figcaption class=\"image-caption block\"><\/figcaption><\/figure>\n\n\n<p><br><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column small-12 medium-4 large-4 pr-12\">\n<h5 class=\"wp-block-heading\">Industries<\/h5>\n\n\n\r\n\t\r\n\t\t<div id=\"block_bd62acf19283e4dee5cf1ddd763a0e73\" class=\"industry-selector \">\r\n\r\n\t\t\t\r\n\t\t\t<a href=\"https:\/\/teoresi.sixeleven.it\/industries\/life-sciences\/\">Life Sciences<\/a>\r\n\t\t<\/div>\r\n\r\n<\/div>\n<\/div>\n\n\n\r\n\t\r\n\t\r\n\t\t<div id=\"block_710fab76060c2aedb7a8694389faca0e\" class=\"storytelling-img mt-16 mb-16 pt-8 pb-8 bg-grey-lightest expanded\">\r\n\r\n\t\t\t<div class=\"row unexpanded\">\r\n\r\n\t\t\t\t<div class=\"column small-12\">\r\n\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"row row-storytelling-img sezione collapse-16 align-center align-middle\">\r\n\r\n\t\t\t\t\t\t\t<div class=\"image column small-12 medium-10 large-7 large-order-2\">\r\n\t\t\t\t\t\t\t\t<div class=\"bg-img b-lazy bg-cover small-ratio-32\" style=\"\" data-src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2024\/09\/ddd-640x480.jpg\" style=\"\" data-paroller-factor=\"0.1\" data-paroller-type=\"background\" data-paroller-direction=\"vertical\" data-paroller-transition=\"transform .1s linear\"><\/div>\t\t\t\t\t\t\t<\/div>\r\n\r\n\r\n\t\t\t\t\t\t\t<div class=\"content column small-12 medium-10 large-5 large-order-1\">\r\n\t\t\t\t\t\t\t\t<div class=\"mb-8\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"title h4 fw-700 color-orange mb-2\">Scenario<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t\t\t<p data-ccp-border-bottom=\"0px none #000000\" data-ccp-padding-bottom=\"0px\" data-ccp-border-between=\"0px none #000000\" data-ccp-padding-between=\"0px\"><span data-contrast=\"auto\">Molecular diagnostics enable accurate and rapid identification of pathogens, as seen in the case of COVID and cervical infections caused by papillomavirus. Today, in screening programs for early and preventive diagnosis of cervical cancer, cytological analysis (Pap test) is increasingly being replaced by the analysis of clinical samples through the amplification of viral genetic material via PCR, as it is more objective and operator independent.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p data-ccp-border-bottom=\"0px none #000000\" data-ccp-padding-bottom=\"0px\" data-ccp-border-between=\"0px none #000000\" data-ccp-padding-between=\"0px\"><span data-contrast=\"auto\">The results, which can be obtained through a combined and sophisticated analysis in terms of reading and interpretation, typically require a high level of operator specialization. The analysis of these multiparametric and quantitative molecular diagnostics results, often involving large sample sizes, greatly benefits from the presence of software that automates the reading, interpretation, and reporting process.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n\t\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t\t<div class=\"line column small-12 large-order-3 mb-0\">\r\n\t\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"row row-storytelling-img sezione collapse-16 align-center align-middle\">\r\n\r\n\t\t\t\t\t\t\t<div class=\"image column small-12 medium-10 large-7 \">\r\n\t\t\t\t\t\t\t\t<div class=\"bg-img b-lazy bg-cover small-ratio-32\" style=\"\" data-src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2024\/09\/dddddd-640x480.jpg\" style=\"\" data-paroller-factor=\"0.1\" data-paroller-type=\"background\" data-paroller-direction=\"vertical\" data-paroller-transition=\"transform .1s linear\"><\/div>\t\t\t\t\t\t\t<\/div>\r\n\r\n\r\n\t\t\t\t\t\t\t<div class=\"content column small-12 medium-10 large-5 \">\r\n\t\t\t\t\t\t\t\t<div class=\"mb-8\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"title h4 fw-700 color-orange mb-2\">Challenges<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t\t\t<p data-ccp-border-bottom=\"0px none #000000\" data-ccp-padding-bottom=\"0px\" data-ccp-border-between=\"0px none #000000\" data-ccp-padding-between=\"0px\">During the project, HiFuture focused on addressing the following challenges:<\/p>\n<ul>\n<li data-ccp-border-bottom=\"0px none #000000\" data-ccp-padding-bottom=\"0px\" data-ccp-border-between=\"0px none #000000\" data-ccp-padding-between=\"0px\"><b><span data-contrast=\"none\">Integration of the new diagnostic software<\/span><\/b><span data-contrast=\"none\"> into the usage process of two innovative analysis kits, with the need to initiate diagnostic protocols across multiple options.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-ccp-border-bottom=\"0px none #000000\" data-ccp-padding-bottom=\"0px\" data-ccp-border-between=\"0px none #000000\" data-ccp-padding-between=\"0px\"><b><span data-contrast=\"none\">Validation and training of the Machine Learning model,<\/span><\/b><span data-contrast=\"none\"> with particular attention to the software&#8217;s flexibility, while maintaining a focus on future developments. These could include new challenges and advancements, such as the addition of further virus types and data from different instruments. The software structure and methodologies developed for HPV can be adapted with minimal modifications to diagnose other viral infections by training new models and generating updated reports.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-ccp-border-bottom=\"0px none #000000\" data-ccp-padding-bottom=\"0px\" data-ccp-border-between=\"0px none #000000\" data-ccp-padding-between=\"0px\"><b><span data-contrast=\"none\">Integration of modularity and interconnectivity features<\/span><\/b><span data-contrast=\"none\"> into the software to ensure and enable easy integration of communication modules with the machines used.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<li data-ccp-border-between=\"0px none #000000\" data-ccp-padding-between=\"0px\"><b><span data-contrast=\"none\">Complete automation of the analytical module\u2019s integration<\/span><\/b><span data-contrast=\"none\"> into the automated diagnostic workflow, which is currently still partially manual.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/li>\n<\/ul>\n\t\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t\t<div class=\"line column small-12 large-order-3 mb-0\">\r\n\t\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\r\n\t\t\t\t<\/div>\r\n\r\n\t\t\t<\/div>\r\n\r\n\t\t<\/div>\r\n\r\n\t\r\n\n\n\n<div class=\"wp-block-columns align-center row sezione\">\n<div class=\"wp-block-column small-12 medium-10 large-8\">\n<h5 class=\"wp-block-heading has-text-align-center\">Our added Value<\/h5>\n\n\n\n<p>The software, developed by HiFuture for Hiantis, allows the parallel processing of clinical sample results and delivers infection and carcinoma risk diagnoses within minutes. The diagnoses are based on a Machine Learning model that has been validated and trained on data manually analyzed by specialists in certified clinical studies. The modularity of the software enables the integration of additional models for different viral pathologies alongside the current papillomavirus model.&nbsp;<\/p>\n\n\n\n<p>HiFuture\u2019s expertise in the design and development process, following biomedical industry regulations, ensured the creation of all necessary documentation for inclusion in the device&#8217;s technical dossier, intending to secure its IVDD certification.<\/p>\n<\/div>\n<\/div>\n\n\n\r\n    <span class=\"block p-4\">&nbsp;<\/span>\r\n\r\n\n\n\n<div class=\"wp-block-columns align-center row sezione\">\n<div class=\"wp-block-column small-12 medium-10 large-8\">\n<h5 class=\"wp-block-heading has-text-align-center\">Results<\/h5>\n\n\n\n<p>The project has achieved the expected results, and the software has been CE-IVD certified. It has been validated against the manual quantitative reading method used as the gold standard and is now undergoing continuous validation by the client.<strong>&nbsp;<\/strong><\/p>\n<\/div>\n<\/div>\n\n\n\r\n    <span class=\"block p-4\">&nbsp;<\/span>\r\n\r\n\n\n\r\n\t7\r\n\r\n\t<div class=\"row sezione align-middle\">\r\n\t\t<div class=\"column small-6\">\r\n\t\t\t\t\t\t\t<span class=\"toptitle fs-xsmall title-line right mb-1\">Projects<\/span>\r\n\t\t\t\t<span class=\"block\"><\/span>\r\n\t\t\t\t\t\t\t\t\t\t<span class=\"title h3 mb-1 dot-after\">Das k\u00f6nnte Sie auch interessieren<\/span>\r\n\t\t\t\t\t\t\t\t<\/div>\r\n\r\n\t\t<div class=\"column small-6 text-right\">\r\n\t\t\t<a class=\"button hollow\" href=\"https:\/\/teoresi.sixeleven.it\/de\/projects\/\">View all<\/a>\r\n\t\t<\/div>\r\n\t<\/div>\r\n\r\n\r\n\t\t<!-- \/\/\/\/\/\/\/\/\/ Slider Posts \/\/\/\/\/\/\/\/\/ -->\r\n\t\t<div id=\"rid568\" class=\"hero-slider row sezione  pt-2 project-slider\">\r\n\r\n\t\t\t<div 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href=\"https:\/\/teoresi.sixeleven.it\/de\/projects\/vree-integrated-home-assistance-adi\/\">\r\n\r\n\t\t<div class=\"figure-container relative small-ratio-43\">\r\n\t\t\t<div class=\"bg-img b-lazy absolute bg-cover overflow-hidden\" style=\"\" data-src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2023\/11\/vree-adi-hero-640x346.jpg\" style=\"absolute\" ><\/div>\t\t<\/div>\r\n\r\n\t\t<div class=\"bg-white p-6 pl-3 pr-3\">\r\n\r\n\t\t\t<span class=\"title h5 mb-3\">VREE Integrated Home Assistance (ADI)<\/span>\r\n\r\n\t\t<\/div>\r\n\r\n\t<\/a>\r\n<\/div>\r\n<\/div><div class=\"swiper-slide\">\r\n<div class=\"column pb-12\">\r\n\t<a href=\"https:\/\/teoresi.sixeleven.it\/de\/projects\/vree-medical-teleconsultation\/\">\r\n\r\n\t\t<div class=\"figure-container relative small-ratio-43\">\r\n\t\t\t<div class=\"bg-img b-lazy absolute bg-cover overflow-hidden\" style=\"\" data-src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2023\/11\/vree-teleconsultationhero-640x235.jpg\" style=\"absolute\" ><\/div>\t\t<\/div>\r\n\r\n\t\t<div class=\"bg-white p-6 pl-3 pr-3\">\r\n\r\n\t\t\t<span class=\"title h5 mb-3\">VREE Medical teleconsultation<\/span>\r\n\r\n\t\t<\/div>\r\n\r\n\t<\/a>\r\n<\/div>\r\n<\/div><div class=\"swiper-slide\">\r\n<div class=\"column pb-12\">\r\n\t<a href=\"https:\/\/teoresi.sixeleven.it\/de\/projects\/nanocan\/\">\r\n\r\n\t\t<div class=\"figure-container relative small-ratio-43\">\r\n\t\t\t<div class=\"bg-img b-lazy absolute bg-cover overflow-hidden\" style=\"\" data-src=\"https:\/\/teoresi.sixeleven.it\/wp-content\/uploads\/2022\/04\/nanocan-hero-640x354.jpg\" style=\"absolute\" ><\/div>\t\t<\/div>\r\n\r\n\t\t<div class=\"bg-white p-6 pl-3 pr-3\">\r\n\r\n\t\t\t<span class=\"title h5 mb-3\">NANOCAN<\/span>\r\n\r\n\t\t<\/div>\r\n\r\n\t<\/a>\r\n<\/div>\r\n<\/div>\t\t\t\t<\/div>\r\n\r\n\t\t\t\t\t\t\t\t\t<div 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